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Alcohol-induced ciliary dysfunction targets the outer dynein arm

Alcohol abuse results in an increased incidence of pulmonary infection, in part attributable to impaired mucociliary clearance. Analysis of motility in mammalian airway cilia has revealed that alcohol impacts the ciliary dynein motors by a mechanism involving altered axonemal protein phosphorylation...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Yang, Fan, Pavlik, Jacqueline, Fox, Laura, Scarbrough, Chasity, Sale, Winfield S., Sisson, Joseph H., Wirschell, Maureen
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360061/
https://ncbi.nlm.nih.gov/pubmed/25595647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00257.2014
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