HCN channel-mediated neuromodulation can control action potential velocity and fidelity in central axons

Hyperpolarization-activated cyclic-nucleotide-gated (HCN) channels control electrical rhythmicity and excitability in the heart and brain, but the function of HCN channels at the subcellular level in axons remains poorly understood. Here, we show that the action potential conduction velocity in both...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Byczkowicz, Niklas, Eshra, Abdelmoneim, Montanaro, Jacqueline, Trevisiol, Andrea, Hirrlinger, Johannes, Kole, Maarten HP, Shigemoto, Ryuichi, Hallermann, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733576/
https://ncbi.nlm.nih.gov/pubmed/31496517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.42766
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