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HCN channel-mediated neuromodulation can control action potential velocity and fidelity in central axons

Hyperpolarization-activated cyclic-nucleotide-gated (HCN) channels control electrical rhythmicity and excitability in the heart and brain, but the function of HCN channels at the subcellular level in axons remains poorly understood. Here, we show that the action potential conduction velocity in both...

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Publicat a:eLife
Autors principals: Byczkowicz, Niklas, Eshra, Abdelmoneim, Montanaro, Jacqueline, Trevisiol, Andrea, Hirrlinger, Johannes, Kole, Maarten HP, Shigemoto, Ryuichi, Hallermann, Stefan
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733576/
https://ncbi.nlm.nih.gov/pubmed/31496517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.42766
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