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HCN channel-mediated neuromodulation can control action potential velocity and fidelity in central axons

Hyperpolarization-activated cyclic-nucleotide-gated (HCN) channels control electrical rhythmicity and excitability in the heart and brain, but the function of HCN channels at the subcellular level in axons remains poorly understood. Here, we show that the action potential conduction velocity in both...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Byczkowicz, Niklas, Eshra, Abdelmoneim, Montanaro, Jacqueline, Trevisiol, Andrea, Hirrlinger, Johannes, Kole, Maarten HP, Shigemoto, Ryuichi, Hallermann, Stefan
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733576/
https://ncbi.nlm.nih.gov/pubmed/31496517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.42766
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