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Sex modulates hepatic mitochondrial adaptations to high-fat diet and physical activity

The impact of sexual dimorphism and mitophagy on hepatic mitochondrial adaptations during the treatment of steatosis with physical activity are largely unknown. Here, we tested if deficiencies in liver-specific peroxisome proliferative activated-receptor-γ coactivator-1α (PGC-1α), a transcriptional...

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Pubblicato in:Am J Physiol Endocrinol Metab
Autori principali: McCoin, Colin S., Von Schulze, Alex, Allen, Julie, Fuller, Kelly N. Z., Xia, Qing, Koestler, Devin C., Houchen, Claire J., Maurer, Adrianna, Dorn, Gerald W., Shankar, Kartik, Morris, E. Matthew, Thyfault, John P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732468/
https://ncbi.nlm.nih.gov/pubmed/31039007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00098.2019
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