Hepatic mitochondrial adaptations to physical activity: impact of sexual dimorphism, PGC1α and BNIP3‐mediated mitophagy

KEY POINTS: Hepatic mitochondrial adaptations to physical activity may be regulated by mitochondrial biogenesis (PGC1α) and mitophagy (BNIP3). Additionally, these adaptations may be sex‐dependent. Chronic increase in physical activity lowers basal mitochondrial respiratory capacity in mice. Female m...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Von Schulze, Alex, McCoin, Colin S., Onyekere, Chiemela, Allen, Julie, Geiger, Paige, Dorn, Gerald W., Morris, E. Matthew, Thyfault, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Exercise
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6292817/
https://ncbi.nlm.nih.gov/pubmed/30062822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP276539
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