Sex and BNIP3 genotype, rather than acute lipid injection, modulate hepatic mitochondrial function and steatosis risk in mice

Both lipid oversupply and poor mitochondrial function (low respiration and elevated H(2)O(2) emission) have been implicated in the development of hepatic steatosis and liver injury. Mitophagy, the targeted degradation of low-functioning mitochondria, is critical for maintaining mitochondrial quality...

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Bibliografiske detaljer
Udgivet i:J Appl Physiol (1985)
Main Authors: Fuller, Kelly N. Z., McCoin, Colin S., Allen, Julie, Bell-Glenn, Shelby, Koestler, Devin C., Dorn, Gerald W., Thyfault, John P.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272752/
https://ncbi.nlm.nih.gov/pubmed/32240015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00035.2020
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