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APOL1 and kidney cell function
The apolipoprotein L1 (APOL1) gene is unique to humans and gorillas and appeared ~33 million years ago. Since the majority of the mammals do not carry APOL1, it seems to be dispensable for kidney function. APOL1 renal risk variants (RRVs; G1 and G2) are associated with the development as well as pro...
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| Veröffentlicht in: | Am J Physiol Renal Physiol |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6732453/ https://ncbi.nlm.nih.gov/pubmed/31241995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00233.2019 |
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