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APOL1 and kidney cell function

The apolipoprotein L1 (APOL1) gene is unique to humans and gorillas and appeared ~33 million years ago. Since the majority of the mammals do not carry APOL1, it seems to be dispensable for kidney function. APOL1 renal risk variants (RRVs; G1 and G2) are associated with the development as well as pro...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Kumar, Vinod, Singhal, Pravin C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732453/
https://ncbi.nlm.nih.gov/pubmed/31241995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00233.2019
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