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APOL1 polymorphisms and kidney disease: loss-of-function or gain-of-function?
The mechanism that explains the association of APOL1 variants with nondiabetic kidney diseases in African Americans remains unclear. Kidney disease risk is inherited as a recessive trait, and many studies investigating the intracellular function of APOL1 have indicated the APOL1 variants G1 and G2 a...
Shranjeno v:
| izdano v: | Am J Physiol Renal Physiol |
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| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Physiological Society
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6383195/ https://ncbi.nlm.nih.gov/pubmed/30332315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00426.2018 |
| Oznake: |
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