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APOL1 and mechanisms of kidney disease susceptibility

PURPOSE OF REVIEW: Allelic variants in the gene for apolipoprotein L1 (APOL1), found only in individuals of African ancestry, explain a majority of the excess risk of kidney disease in African Americans. However, a clear understanding how the disease-associated APOL1 variants cause kidney injury and...

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Détails bibliographiques
Publié dans:Curr Opin Nephrol Hypertens
Auteurs principaux: Bruggeman, Leslie A., Sedor, John R., O’Toole, John F.
Format: Artigo
Langue:Inglês
Publié: 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8211384/
https://ncbi.nlm.nih.gov/pubmed/33767059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MNH.0000000000000704
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