MCP-1 promotes detrimental cardiac physiology, pulmonary edema, and death in the cpk model of polycystic kidney disease

Polycystic kidney disease (PKD) is characterized by slowly expanding renal cysts that damage the kidney, typically resulting in renal failure by the fifth decade. The most common cause of death in these patients, however, is cardiovascular disease. Expanding cysts in PKD induce chronic kidney injury...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Salah, Sally M., Meisenheimer, James D., Rao, Reena, Peda, Jacqueline D., Wallace, Darren P., Foster, Dawson, Li, Xiaogang, Li, Xiaoyan, Zhou, Xia, Vallejo, Julian A., Wacker, Michael J., Fields, Timothy A., Swenson-Fields, Katherine I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732452/
https://ncbi.nlm.nih.gov/pubmed/31091126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00240.2018
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