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Acceleration of polycystic kidney disease progression in cpk mice carrying a deletion in the homeodomain protein Cux1

Polycystic kidney diseases (PKD) are inherited as autosomal dominant (ADPKD) or autosomal recessive (ARPKD) traits and are characterized by progressive enlargement of renal cysts. Aberrant cell proliferation is a key feature in the progression of PKD. Cux1 is a homeobox gene that is related to Droso...

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Main Authors: Alcalay, Neal I., Sharma, Madhulika, Vassmer, Dianne, Chapman, Brandon, Paul, Binu, Zhou, Jing, Brantley, Jennifer G., Wallace, Darren P., Maser, Robin L., Vanden Heuvel, Gregory B.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604819/
https://ncbi.nlm.nih.gov/pubmed/18829740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90420.2008
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