Cux1 promotes cell proliferation and polycystic kidney disease progression in an ADPKD mouse model

Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common monogenic hereditary disorders in humans characterized by fluid-filled cysts, primarily in the kidneys. Cux1, a cell cycle regulatory gene highly expressed during kidney development, is elevated in the cyst-lining cells o...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Porath, Binu, Livingston, Safia, Andres, Erica L., Petrie, Alexandra M., Wright, Joshua C., Woo, Anna E., Carlton, Carol G., Baybutt, Richard, Vanden Heuvel, Gregory B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668583/
https://ncbi.nlm.nih.gov/pubmed/28701314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00380.2016
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