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Cux1 promotes cell proliferation and polycystic kidney disease progression in an ADPKD mouse model
Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common monogenic hereditary disorders in humans characterized by fluid-filled cysts, primarily in the kidneys. Cux1, a cell cycle regulatory gene highly expressed during kidney development, is elevated in the cyst-lining cells o...
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| Izdano u: | Am J Physiol Renal Physiol |
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| Glavni autori: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Physiological Society
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5668583/ https://ncbi.nlm.nih.gov/pubmed/28701314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00380.2016 |
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