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Loss of acid-sensing ion channel 2 enhances pulmonary vascular resistance and hypoxic pulmonary hypertension

Acid-sensing ion channels (ASICs) are voltage-insensitive cation channels that contribute to cellular excitability. We previously reported that ASIC1 in pulmonary artery smooth muscle cells (PASMC) contribute to pulmonary vasoreactivity and vascular remodeling during the development of chronic hypox...

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Detalhes bibliográficos
Publicado no:J Appl Physiol (1985)
Main Authors: Detweiler, Neil D., Herbert, Lindsay M., Garcia, Selina M., Yan, Simin, Vigil, Kenneth G., Sheak, Joshua R., Resta, Thomas C., Walker, Benjimen R., Jernigan, Nikki L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732443/
https://ncbi.nlm.nih.gov/pubmed/31169471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00894.2018
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