Loss of acid-sensing ion channel 2 enhances pulmonary vascular resistance and hypoxic pulmonary hypertension

Acid-sensing ion channels (ASICs) are voltage-insensitive cation channels that contribute to cellular excitability. We previously reported that ASIC1 in pulmonary artery smooth muscle cells (PASMC) contribute to pulmonary vasoreactivity and vascular remodeling during the development of chronic hypox...

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Veröffentlicht in:J Appl Physiol (1985)
Hauptverfasser: Detweiler, Neil D., Herbert, Lindsay M., Garcia, Selina M., Yan, Simin, Vigil, Kenneth G., Sheak, Joshua R., Resta, Thomas C., Walker, Benjimen R., Jernigan, Nikki L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2019
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732443/
https://ncbi.nlm.nih.gov/pubmed/31169471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00894.2018
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