Loss of acid-sensing ion channel 2 enhances pulmonary vascular resistance and hypoxic pulmonary hypertension

Acid-sensing ion channels (ASICs) are voltage-insensitive cation channels that contribute to cellular excitability. We previously reported that ASIC1 in pulmonary artery smooth muscle cells (PASMC) contribute to pulmonary vasoreactivity and vascular remodeling during the development of chronic hypox...

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Pubblicato in:J Appl Physiol (1985)
Autori principali: Detweiler, Neil D., Herbert, Lindsay M., Garcia, Selina M., Yan, Simin, Vigil, Kenneth G., Sheak, Joshua R., Resta, Thomas C., Walker, Benjimen R., Jernigan, Nikki L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732443/
https://ncbi.nlm.nih.gov/pubmed/31169471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00894.2018
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