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Diaphragm contractile weakness due to reduced mechanical loading: role of titin

The diaphragm, the main muscle of inspiration, is constantly subjected to mechanical loading. Only during controlled mechanical ventilation, as occurs during thoracic surgery and in the intensive care unit, is mechanical loading of the diaphragm arrested. Animal studies indicate that the diaphragm i...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: van der Pijl, Robbert J., Granzier, Henk L., Ottenheijm, Coen A. C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732419/
https://ncbi.nlm.nih.gov/pubmed/31042425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00509.2018
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