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Prediction of Orthosteric and Allosteric Regulations on Cannabinoid Receptors Using Supervised Machine Learning Classifiers

Designing highly selective compounds to protein subtypes and developing allosteric modulators targeting them are critical considerations to both drug discovery and mechanism studies for cannabinoid receptors. It is challenging but in demand to have classifiers to identify active ligands from inactiv...

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書目詳細資料
發表在:Mol Pharm
Main Authors: Bian, Yuemin, Jing, Yankang, Wang, Lirong, Ma, Shifan, Jun, Jaden Jungho, Xie, Xiang-Qun
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732211/
https://ncbi.nlm.nih.gov/pubmed/31013097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.9b00182
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