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Cell phenotypic plasticity requires autophagic flux driven by YAP/TAZ mechanotransduction

Autophagy, besides ensuring energy metabolism and organelle renewal, is crucial for the biology of adult normal and cancer stem cells. However, it remains incompletely understood how autophagy connects to stemness factors and the nature of the microenvironmental signals that pattern autophagy in dif...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Totaro, Antonio, Zhuang, Qiuyu, Panciera, Tito, Battilana, Giusy, Azzolin, Luca, Brumana, Giulia, Gandin, Alessandro, Brusatin, Giovanna, Cordenonsi, Michelangelo, Piccolo, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731754/
https://ncbi.nlm.nih.gov/pubmed/31416916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1908228116
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