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De Novo Generation of Somatic Stem Cells by YAP/TAZ

Here we present protocols to isolate primary differentiated cells and turn them into stem/progenitor cells (SCs) of the same lineage by transient expression of the transcription factor YAP. With this method, luminal differentiated (LD) cells of the mouse mammary gland are converted into cells that e...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Panciera, Tito, Azzolin, Luca, Di Biagio, Daniele, Totaro, Antonio, Cordenonsi, Michelangelo, Piccolo, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101120/
https://ncbi.nlm.nih.gov/pubmed/29782008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57462
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