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De Novo Generation of Somatic Stem Cells by YAP/TAZ

Here we present protocols to isolate primary differentiated cells and turn them into stem/progenitor cells (SCs) of the same lineage by transient expression of the transcription factor YAP. With this method, luminal differentiated (LD) cells of the mouse mammary gland are converted into cells that e...

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Détails bibliographiques
Publié dans:J Vis Exp
Auteurs principaux: Panciera, Tito, Azzolin, Luca, Di Biagio, Daniele, Totaro, Antonio, Cordenonsi, Michelangelo, Piccolo, Stefano
Format: Artigo
Langue:Inglês
Publié: MyJove Corporation 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101120/
https://ncbi.nlm.nih.gov/pubmed/29782008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57462
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