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Mitochondrial transcription factor A promotes DNA strand cleavage at abasic sites

In higher eukaryotic cells, mitochondria are essential subcellular organelles for energy production, cell signaling, and the biosynthesis of biomolecules. The mitochondrial DNA (mtDNA) genome is indispensable for mitochondrial function because it encodes protein subunits of the electron transport ch...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Xu, Wenyan, Boyd, Riley M., Tree, Maya O., Samkari, Faris, Zhao, Linlin
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731678/
https://ncbi.nlm.nih.gov/pubmed/31413200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1911252116
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