Oncogenic MYC amplifies mitotic perturbations

The oncogenic transcription factor MYC modulates vast arrays of genes, thereby influencing numerous biological pathways including biogenesis, metabolism, proliferation, apoptosis and pluripotency. When deregulated, MYC drives genomic instability via several mechanisms including aberrant proliferatio...

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Detalles Bibliográficos
Publicado en:Open Biol
Autores principales: Littler, Samantha, Sloss, Olivia, Geary, Bethany, Pierce, Andrew, Whetton, Anthony D., Taylor, Stephen S.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Royal Society 2019
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731591/
https://ncbi.nlm.nih.gov/pubmed/31455158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.190136
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