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Inhibition of Bcl-xL sensitizes cells to mitotic blockers, but not mitotic drivers

Cell fate in response to an aberrant mitosis is governed by two competing networks: the spindle assembly checkpoint (SAC) and the intrinsic apoptosis pathway. The mechanistic interplay between these two networks is obscured by functional redundancy and the ability of cells to die either in mitosis o...

詳細記述

保存先:
書誌詳細
出版年:Open Biol
主要な著者: Bennett, Ailsa, Sloss, Olivia, Topham, Caroline, Nelson, Louisa, Tighe, Anthony, Taylor, Stephen S.
フォーマット: Artigo
言語:Inglês
出版事項: The Royal Society 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008013/
https://ncbi.nlm.nih.gov/pubmed/27512141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.160134
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