Pharmacological inhibition of Bcl-xL sensitizes osteosarcoma to doxorubicin

High-grade conventional osteosarcoma is the most common primary bone tumor. Prognosis for osteosarcoma patients is poor and resistance to chemotherapy is common. We performed an siRNA screen targeting members of the Bcl-2 family in human osteosarcoma cell lines to identify critical regulators of ost...

詳細記述

保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Baranski, Zuzanna, de Jong, Yvonne, Ilkova, Trayana, Peterse, Elisabeth F.P., Cleton-Jansen, Anne-Marie, van de Water, Bob, Hogendoorn, Pancras C.W., Bovée, Judith V.M.G., Danen, Erik H.J.
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2015
主題:
Research Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742165/
https://ncbi.nlm.nih.gov/pubmed/26416351
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