MYC Is a Major Determinant of Mitotic Cell Fate

Taxol and other antimitotic agents are frontline chemotherapy agents but the mechanisms responsible for patient benefit remain unclear. Following a genome-wide siRNA screen, we identified the oncogenic transcription factor Myc as a taxol sensitizer. Using time-lapse imaging to correlate mitotic beha...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cancer Cell
Autori principali: Topham, Caroline, Tighe, Anthony, Ly, Peter, Bennett, Ailsa, Sloss, Olivia, Nelson, Louisa, Ridgway, Rachel A., Huels, David, Littler, Samantha, Schandl, Claudia, Sun, Ying, Bechi, Beatrice, Procter, David J., Sansom, Owen J., Cleveland, Don W., Taylor, Stephen S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2015
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518499/
https://ncbi.nlm.nih.gov/pubmed/26175417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2015.06.001
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi