International Union of Basic and Clinical Pharmacology. CVII. Structure and Pharmacology of the Apelin Receptor with a Recommendation that Elabela/Toddler Is a Second Endogenous Peptide Ligand

The predicted protein encoded by the APJ gene discovered in 1993 was originally classified as a class A G protein-coupled orphan receptor but was subsequently paired with a novel peptide ligand, apelin-36 in 1998. Substantial research identified a family of shorter peptides activating the apelin rec...

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Detalhes bibliográficos
Publicado no:Pharmacol Rev
Main Authors: Read, Cai, Nyimanu, Duuamene, Williams, Thomas L., Huggins, David J., Sulentic, Petra, Macrae, Robyn G. C., Yang, Peiran, Glen, Robert C., Maguire, Janet J., Davenport, Anthony P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2019
Assuntos:
IUPHAR Nomenclature Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731456/
https://ncbi.nlm.nih.gov/pubmed/31492821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.119.017533
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