EBV Latency III–Transformed B Cells Are Inducers of Conventional and Unconventional Regulatory T Cells in a PD-L1–Dependent Manner

EBV infects and immortalizes B cells in vitro and in vivo. It is the causative agent of most immune deficiency–related lymphoproliferative disorders and is associated with various lymphomas. EBV latency III–transformed B cells are known to express two immunosuppressive molecules, IL-10 and PD-L1, tw...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Auclair, Héloïse, Ouk-Martin, Catherine, Roland, Lilian, Santa, Pauline, Al Mohamad, Hazar, Faumont, Nathalie, Feuillard, Jean, Jayat-Vignoles, Chantal
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2019
Assuntos:
Tumor Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731452/
https://ncbi.nlm.nih.gov/pubmed/31434708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801420
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