Molecular Basis of Cytotoxicity of Epstein-Barr Virus (EBV) Latent Membrane Protein 1 (LMP1) in EBV Latency III B Cells: LMP1 Induces Type II Ligand-Independent Autoactivation of CD95/Fas with Caspase 8-Mediated Apoptosis

The Epstein-Barr virus (EBV) oncoprotein latent membrane protein 1 (LMP1) is thought to act as the major transforming protein in various cell types, by rerouting the tumor necrosis factor receptor family signaling pathway. Despite this implication in EBV-associated transformation of cells, LMP1 toxi...

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Detalhes bibliográficos
Main Authors: Le Clorennec, Christophe, Ouk, Tan-Sothéa, Youlyouz-Marfak, Ibtissam, Panteix, Stéphanie, Martin, Catherine-Claude, Rastelli, Julia, Adriaenssens, Eric, Zimber-Strobl, Ursula, Coll, Jean, Feuillard, Jean, Jayat-Vignoles, Chantal
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447067/
https://ncbi.nlm.nih.gov/pubmed/18448526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02250-07
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