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Escin protects against acetaminophen-induced liver injury in mice via attenuating inflammatory response and inhibiting ERK signaling pathway

Acetaminophen (APAP) overdose may lead to the formation of oxidative stress, hepatocyte apoptosis and necrosis, and, eventually result in acute liver failure. Escin, a major extracted component of Aesculus hippocastanum, reportedly exerts anti-inflammatory, anti-edematous and anti-oxidant properties...

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Bibliografiske detaljer
Udgivet i:Am J Transl Res
Main Authors: Lee, Hung-Chen, Yu, Huang-Ping, Liao, Chia-Chih, Chou, An-Hsun, Liu, Fu-Chao
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731419/
https://ncbi.nlm.nih.gov/pubmed/31497232
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