Escin protects against acetaminophen-induced liver injury in mice via attenuating inflammatory response and inhibiting ERK signaling pathway

Acetaminophen (APAP) overdose may lead to the formation of oxidative stress, hepatocyte apoptosis and necrosis, and, eventually result in acute liver failure. Escin, a major extracted component of Aesculus hippocastanum, reportedly exerts anti-inflammatory, anti-edematous and anti-oxidant properties...

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Vydáno v:Am J Transl Res
Hlavní autoři: Lee, Hung-Chen, Yu, Huang-Ping, Liao, Chia-Chih, Chou, An-Hsun, Liu, Fu-Chao
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2019
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731419/
https://ncbi.nlm.nih.gov/pubmed/31497232
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