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Etoposide-induced DNA damage in a chromosomal breakpoint of RUNX1 gene is independent of RUNX1 expression

In this work, we analyzed the association between RUNX1 gene expression and the accessibility of BCR3, one of RUNX1 gene breakpoint regions involved in the chromosomal translocation (8;21), a frequent translocation in treatment-related acute myeloid leukemia patients. To this end, we evaluate DNA da...

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Bibliografiske detaljer
Udgivet i:Leuk Res Rep
Main Authors: Schnake, Nicolás, Gutiérrez, Soraya
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731348/
https://ncbi.nlm.nih.gov/pubmed/31516823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lrr.2019.100182
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