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Etoposide-induced DNA damage in a chromosomal breakpoint of RUNX1 gene is independent of RUNX1 expression

In this work, we analyzed the association between RUNX1 gene expression and the accessibility of BCR3, one of RUNX1 gene breakpoint regions involved in the chromosomal translocation (8;21), a frequent translocation in treatment-related acute myeloid leukemia patients. To this end, we evaluate DNA da...

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Detalhes bibliográficos
Publicado no:Leuk Res Rep
Main Authors: Schnake, Nicolás, Gutiérrez, Soraya
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731348/
https://ncbi.nlm.nih.gov/pubmed/31516823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lrr.2019.100182
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