Systemic delivery and SPECT/CT in vivo imaging of (125)I-labelled oncolytic adenoviral mutants in models of pancreatic cancer

Early phase clinical trials have demonstrated good therapeutic index for oncolytic adenoviruses in patients with solid tumours when administered intratumorally, resulting in local tumour elimination. Entrapment and binding of adenovirus to erythrocytes, blood factors, and neutralising antibodies hav...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Stella Man, Y. K., Foster, Julie, Carapuça, Elisabete, Davies, James A., Parker, Alan L., Sosabowski, Jane, Halldén, Gunnel
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731255/
https://ncbi.nlm.nih.gov/pubmed/31492884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49150-9
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