Synergistic and Selective Cancer Cell Killing Mediated by the Oncolytic Adenoviral Mutant AdΔΔ and Dietary Phytochemicals in Prostate Cancer Models

AdΔΔ is an oncolytic adenoviral mutant that has been engineered to selectively target tumors with deregulated cell cycle and apoptosis pathways. AdΔΔ potentiates apoptotic cell death induced by drugs, including mitoxantrone and docetaxel, which are commonly used to treat prostate cancer. Here, we de...

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Autores principales: Adam, Virginie, Ekblad, Maria, Sweeney, Katrina, Müller, Heike, Busch, Kristina Hammarén, Johnsen, Camilla Tørnqvist, Kang, Na Ra, Lemoine, Nick R., Halldén, Gunnel
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2012
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440020/
https://ncbi.nlm.nih.gov/pubmed/22788991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2012.046
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