Synergistic and Selective Cancer Cell Killing Mediated by the Oncolytic Adenoviral Mutant AdΔΔ and Dietary Phytochemicals in Prostate Cancer Models

AdΔΔ is an oncolytic adenoviral mutant that has been engineered to selectively target tumors with deregulated cell cycle and apoptosis pathways. AdΔΔ potentiates apoptotic cell death induced by drugs, including mitoxantrone and docetaxel, which are commonly used to treat prostate cancer. Here, we de...

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Main Authors: Adam, Virginie, Ekblad, Maria, Sweeney, Katrina, Müller, Heike, Busch, Kristina Hammarén, Johnsen, Camilla Tørnqvist, Kang, Na Ra, Lemoine, Nick R., Halldén, Gunnel
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2012
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440020/
https://ncbi.nlm.nih.gov/pubmed/22788991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2012.046
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