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Tamoxifen suppresses pancreatic β-cell proliferation in mice
Tamoxifen is a mixed agonist/antagonist estrogen analogue that is frequently used to induce conditional gene deletion in mice using Cre-loxP mediated gene recombination. Tamoxifen is routinely employed in extremely high-doses relative to typical human doses to induce efficient gene deletion in mice....
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| Vydáno v: | PLoS One |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6731016/ https://ncbi.nlm.nih.gov/pubmed/31490929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214829 |
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