Incretin Therapies Do Not Expand β-Cell Mass or Alter Pancreatic Histology in Young Male Mice

The impact of incretins upon pancreatic β-cell expansion remains extremely controversial. Multiple studies indicate that incretin-based therapies can increase β-cell proliferation, and incretins have been hypothesized to expand β-cell mass. However, disagreement exists on whether incretins increase...

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Bibliographic Details
Published in:Endocrinology
Main Authors: Cox, Aaron R., Lam, Carol J., Rankin, Matthew M., Rios, Jacqueline S., Chavez, Julia, Bonnyman, Claire W., King, Kourtney B., Wells, Roger A., Anthony, Deepti, Tu, Justin X., Kim, Jenny J., Li, Changhong, Kushner, Jake A.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2017
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460937/
https://ncbi.nlm.nih.gov/pubmed/28323942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00027
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