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Mechanistic studies on the absorption enhancement of a self-nanoemulsifying drug delivery system loaded with norisoboldine-phospholipid complex
BACKGROUND: Norisoboldine (NOR), the main isoquinoline alkaloid constituent in Radix Linderae, was demonstrated to have an outstanding anti-arthritis activity. However, a poor oral bioavailability of NOR creates a barrier for its development and application. METHODS: A new self-nanoemulsifying drug...
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| Veröffentlicht in: | Int J Nanomedicine |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Dove
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6730610/ https://ncbi.nlm.nih.gov/pubmed/31564867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S211905 |
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