Preparation and evaluation of a self-nanoemulsifying drug delivery system loaded with Akebia saponin D–phospholipid complex

BACKGROUND: Akebia saponin D (ASD) exerts various pharmacological activities but with poor oral bioavailability. In this study, a self-nanoemulsifying drug delivery system (SNEDDS) based on the drug–phospholipid complex technique was developed to improve the oral absorption of ASD. METHODS: ASD–phos...

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Vydáno v:Int J Nanomedicine
Hlavní autoři: Shen, Jinyang, Bi, Jianping, Tian, Hongli, Jin, Ye, Wang, Yuan, Yang, Xiaolin, Yang, Zhonglin, Kou, Junping, Li, Fei
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2016
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045231/
https://ncbi.nlm.nih.gov/pubmed/27713630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S108765
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