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Integration of phospholipid-drug complex into self-nanoemulsifying drug delivery system to facilitate oral delivery of paclitaxel

Self-nanoemulsifying drug delivery system (SNEDDS) has emerged as a promising platform to improve oral absorption of drugs with poor solubility and low permeability. However, large polarity molecules with insufficient lipid solubility, such as paclitaxel (PTX), would suffer from inferior formulation...

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Bibliografische Detailangaben
Hauptverfasser: Dawei Ding, Bingjun Sun, Weiping Cui, Qin Chen, Xuanbo Zhang, Haotian Zhang, Zhonggui He, Jin Sun, Cong Luo
Format: Artigo
Sprache:Inglês
Veröffentlicht: KeAi Communications Co., Ltd. 2019-09-01
Schriftenreihe:Asian Journal of Pharmaceutical Sciences
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S181808761830610X
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