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Heat Shock Protein 70 Participates in the Neuroprotective Response to Intracellularly Expressed β-Amyloid in Neurons

Intracellular β-amyloid 42 (Aβ42) accumulation is increasingly recognized as an early event in the pathogenesis of Alzheimer's disease (AD). We have developed a doxycycline-inducible adenoviral-based system that directs intracellular Aβ42 expression and accumulation into the endoplasmic reticul...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Magrané, Jordi, Smith, Roy C., Walsh, Kenneth, Querfurth, Henry W.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730449/
https://ncbi.nlm.nih.gov/pubmed/14973234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4330-03.2004
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