Propofol Restores the Function of “Hyperekplexic” Mutant Glycine Receptors in Xenopus Oocytes and Mice

Human hereditary hyperekplexia (“startle disease”) is a neurological disorder characterized by exaggerated, convulsive movements in response to unexpected stimuli. Molecular genetic studies have shown that this disease is often caused by amino acid substitutions at arginine 271 to glutamine or leuci...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: O'Shea, Sean Michael, Becker, Lore, Weiher, Hans, Betz, Heinrich, Laube, Bodo
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730415/
https://ncbi.nlm.nih.gov/pubmed/14999083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4675-03.2004
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