PHCCC, a Specific Enhancer of Type 4 Metabotropic Glutamate Receptors, Reduces Proliferation and Promotes Differentiation of Cerebellar Granule Cell Neuroprecursors

Exposure of immature rat cerebellar granule cell cultures to the type 4 metabotropic glutamate (mGlu4) receptor enhancer N-phenyl-7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxamide (PHCCC) reduced [(3)H]thymidine incorporation. Its action was sensitive to the growth conditions and was attenuated by...

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Udgivet i:J Neurosci
Main Authors: Canudas, A. M., Di Giorgi-Gerevini, V., Iacovelli, L., Nano, G., D'Onofrio, M., Arcella, A., Giangaspero, F., Busceti, C., Ricci-Vitiani, L., Battaglia, G., Nicoletti, F., Melchiorri, D.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2004
Fag:
Development/Plasticity/Repair
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730308/
https://ncbi.nlm.nih.gov/pubmed/15548648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3229-04.2004
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