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Insulin-Degrading Enzyme as a Downstream Target of Insulin Receptor Signaling Cascade: Implications for Alzheimer's Disease Intervention
Insulin-degrading enzyme (IDE) is one of the proteins that has been demonstrated to play a key role in degrading β-amyloid (Aβ) monomer in vitro and in vivo, raising the possibility of upregulating IDE as an approach to reduce Aβ. Little is known, however, about the cellular and molecular regulation...
محفوظ في:
| الحاوية / القاعدة: | J Neurosci |
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| المؤلفون الرئيسيون: | , , , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Society for Neuroscience
2004
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6730264/ https://ncbi.nlm.nih.gov/pubmed/15590928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2860-04.2004 |
| الوسوم: |
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