Caspase-7 Expanded Function and Intrinsic Expression Level Underlies Strain-Specific Brain Phenotype of Caspase-3-Null Mice

Caspase-3-deficient mice of the 129S1/SvImJ (129) strain show severe brain development defects resulting in brain overgrowth and perinatal lethality, whereas on the C57BL/6J (B6) background, these mice develop normally. We therefore sought to identify the strain-dependent ameliorating gene. We bioch...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Houde, Caroline, Banks, Kathleen G., Coulombe, Nathalie, Rasper, Dita, Grimm, Erich, Roy, Sophie, Simpson, Elizabeth M., Nicholson, Donald W.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2004
Assuntos:
Development/Plasticity/Repair
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730247/
https://ncbi.nlm.nih.gov/pubmed/15525783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3356-04.2004
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