Loading...
Caspase Inhibitors Attenuate 1-Methyl-4-Phenylpyridinium Toxicity in Primary Cultures of Mesencephalic Dopaminergic Neurons
Parkinson's disease is characterized by a loss of dopaminergic nigrostriatal neurons. This neuronal loss is mimicked by the neurotoxin 1-methyl-4-phenylpyridinium (MPP(+)). MPP(+) toxicity is mediated through inhibition of mitochondrial complex I, decreasing ATP production, and upregulation of...
Na minha lista:
| Udgivet i: | J Neurosci |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Society for Neuroscience
2002
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6758313/ https://ncbi.nlm.nih.gov/pubmed/11923429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-07-02637.2002 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|