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Failed Clearance of Aneuploid Embryonic Neural Progenitor Cells Leads to Excess Aneuploidy in the Atm-Deficient But Not the Trp53-Deficient Adult Cerebral Cortex

Aneuploid neurons populate the normal adult brain, but the cause and the consequence of chromosome abnormalities in the CNS are poorly defined. In the adult cerebral cortex of three genetic mutants, one of which is a mouse model of the human neurodegenerative disease ataxia-telangiectasia (A-T), we...

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Bibliografski detalji
Izdano u:J Neurosci
Glavni autori: McConnell, Michael J., Kaushal, Dhruv, Yang, Amy H., Kingsbury, Marcy A., Rehen, Stevens K., Treuner, Kai, Helton, Robert, Annas, Emily G., Chun, Jerold, Barlow, Carrolee
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2004
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729802/
https://ncbi.nlm.nih.gov/pubmed/15371510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2263-04.2004
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