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Chromosomal variation in neurons of the developing and adult mammalian nervous system

A basic assumption about the normal nervous system is that its neurons possess identical genomes. Here we present direct evidence for genomic variability, manifested as chromosomal aneuploidy, among developing and mature neurons. Analysis of mouse embryonic cerebral cortical neuroblasts in situ dete...

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Detalhes bibliográficos
Main Authors: Rehen, Stevens Kastrup, McConnell, Michael J., Kaushal, Dhruv, Kingsbury, Marcy A., Yang, Amy H., Chun, Jerold
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC60876/
https://ncbi.nlm.nih.gov/pubmed/11698687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.231487398
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