Neuroprotective Function of the PGE(2) EP2 Receptor in Cerebral Ischemia

The cyclooxygenases COX-1 and COX-2 catalyze the first committed step of prostaglandin synthesis from arachidonic acid. Previous studies in rodent stroke models have shown that the inducible COX-2 isoform promotes neuronal injury, and the administration of COX-2 inhibitors reduces infarct volume. We...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: McCullough, Louise, Wu, Liejun, Haughey, Norman, Liang, Xibin, Hand, Tracey, Wang, Qian, Breyer, Richard M., Andreasson, Katrin
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729582/
https://ncbi.nlm.nih.gov/pubmed/14715958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4485-03.2004
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