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Misoprostol, an anti-ulcer agent and PGE(2) receptor agonist, protects against cerebral ischemia
Induction of COX-2 activity in cerebral ischemia results in increased neuronal injury and infarct size. Recent studies investigating neurotoxic mechanisms of COX-2 demonstrate both toxic and paradoxically protective effects of downstream prostaglandin receptor signaling pathways. We tested whether m...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2621308/ https://ncbi.nlm.nih.gov/pubmed/18472336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2008.04.054 |
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